Thermo Fisher Scientific TRPC5 Monoclonal Antibody (N67/15)
TRPC5 단백질을 검출하는 Mouse monoclonal antibody (Clone N67/15). Western blot, IHC, IP 등 다양한 응용 가능. Human, Mouse, Rat 반응성. Protein G 정제, PBS 버퍼에 50% glycerol 함유. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunoprecipitation (IP) | Assay-dependent |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N67/15 |
| Immunogen | Synthetic peptide amino acids 827–845 of human TrpC5 (short transient receptor potential channel 5, Htrp5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2735399 |
Additional Formats
Product Specific Information
Formerly sold as clone (S67/15).
1 µg/mL of MA5-27657 was sufficient for detection of TrpC5 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 110 kDa.
Target Information
TRPC5 belongs to the transient receptor family and is one of seven mammalian TRPC proteins.
It forms a receptor-activated non-selective calcium permeant cation channel and can act alone or as a heteromultimer with TRPC1, TRPC3, and TRPC4.
TRPC5 interacts with calmodulin, CABP1, enkurin, NHERF, MX1, RNF24, and SESTD1.
It operates via phosphatidylinositol second messenger systems activated by receptor tyrosine kinases or G-protein coupled receptors.
TRPC5 may also be activated by intracellular calcium store depletion.
Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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