
Thermo Fisher Scientific HOXD10 Monoclonal Antibody (OTI1D11), TrueMAB
Human HOXD10 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot 및 IHC(P) 적용 가능. 고순도 친화 크로마토그래피 정제, 동결건조 형태. 연구용으로만 사용되며, 재구성 및 결합 실험에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 80–340 of human HOXD10 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
HOXD10 is a member of the Abd-B homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain.
It is part of the homeobox D gene cluster on chromosome 2 and functions as a sequence-specific transcription factor involved in limb bud development and differentiation.
Mutations in HOXD10 are associated with Wilms’ tumor and congenital vertical talus, as well as foot deformities similar to Charcot-Marie-Tooth disease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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