Thermo Fisher Scientific CENPJ Monoclonal Antibody (OTI1E3), TrueMAB
CENPJ 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot에 최적화됨. 인간 시료에 반응하며, 고순도 친화성 크로마토그래피 정제 제품. PBS/BSA/glycerol 저장용액 형태로 안정적이며 연구용으로 적합.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1087–1338 of human CENPJ produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in maintaining centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome.
It can function as a transcriptional coactivator in the Stat5 signaling pathway and as a coactivator of NF-kappaB-mediated transcription via interaction with the coactivator p300/CREB-binding protein.
Mutations in this gene are associated with primary autosomal recessive microcephaly, characterized by severely reduced brain size and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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