Thermo Fisher Scientific CENPJ Monoclonal Antibody (OTI3G8), TrueMAB
CENPJ 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 최적화되어 있습니다. Human 시료에 반응하며, TrueMAB 형식으로 고순도 정제되었습니다. PBS/BSA/glycerol buffer에 보관되며 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1087–1338 of human CENPJ produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CENPJ gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in maintaining centrosome integrity and normal spindle morphology and is involved in microtubule disassembly at the centrosome. It can function as a transcriptional coactivator in the Stat5 signaling pathway and as a coactivator of NF-kappaB-mediated transcription, likely via interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, characterized by reduced brain size and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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