Thermo Fisher Scientific CD205 Monoclonal Antibody (205yekta), Biotin, eBioscience
마우스 CD205(DEC-205)을 인식하는 단클론 항체로, 항원 포획 및 제시 연구에 적합합니다. Biotin 결합 형식이며, 유세포 분석(Flow Cytometry)에 최적화되었습니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, 4°C 보관 권장.
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- 판매단위
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | ≤ 0.015 µg/test |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), Biotin, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 205yekta |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1210594 |
Additional Formats Available
- Alexa Fluor 488
- APC
- NovaFluor Blue 660-120S
- NovaFluor Red 685
- NovaFluor Red 700
- NovaFluor Red 755
- NovaFluor Yellow 610
- NovaFluor Yellow 660
- NovaFluor Yellow 700
- NovaFluor Yellow 755
- PE
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 600
- Super Bright 645
- Request custom conjugation
Product Specific Information
Description:
The 205yekta antibody reacts with mouse CD205 (DEC-205), a 205 kDa integral membrane glycoprotein involved in antigen uptake, trafficking, and presentation. CD205 enhances antigen-specific T cell immunity and is highly expressed by CD8⁺ dendritic cells, with variable expression in bone marrow Gr1⁺ cells, Langerhans cells, BMDCs, and thymic epithelial cells.
Note: CD205 binds to PE-Cy5.5 antibody and streptavidin conjugates; therefore, this biotin format should not be used on CD205⁺ dendritic cells.
Applications Reported:
Suitable for flow cytometric analysis.
Applications Tested:
Tested on mouse bone marrow cells. Recommended ≤ 0.015 µg/test in 100 µL final volume. Optimal titration is advised for specific assays.
Filtration:
0.2 µm post-manufacturing filtered.
Target Information
CD205 (LY25, Lymphocyte Antigen 75) is a membrane glycoprotein involved in antigen uptake and presentation, enhancing antigen-specific T cell responses. It functions as an endocytic receptor directing antigens to specialized processing regions and can modulate B lymphocyte proliferation. CD205 dysfunction has been linked to pneumonic plague and lipid pneumonia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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