Thermo Fisher Scientific C8orf4 Polyclonal Antibody
C8orf4 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC(P)에서 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 순도(>95%) 보유. 인간, 생쥐, 랫트 반응성. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human C8orf4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719923 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
The C8orf4 gene encodes a small, monomeric, and predominantly unstructured protein that functions as a positive regulator of the Wnt/β-catenin signaling pathway. This protein interacts with a repressor of β-catenin–mediated transcription at nuclear speckles, competitively blocking repressor interactions with β-catenin and thereby upregulating β-catenin target genes. It may also be involved in NF-κB and ERK1/2 signaling pathways. Expression of this gene has been implicated in the proliferation of several cancers, including thyroid, breast, and hematological malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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