Thermo Fisher Scientific LGI1 Polyclonal Antibody
Thermo Fisher Scientific의 LGI1 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 비결합 항체로, 신경 관련 단백질 LGI1 연구에 유용합니다. 냉장 또는 냉동 보관이 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution
- 1 µg/mL
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 13 amino acid peptide from near the amino terminus of human LGI1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153600 |
Product Specific Information
- A suggested positive control is mouse brain tissue lysate.
- PA5-20506 can be used with blocking peptide PEP-0626.
Target Information
The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs), which are similar to transmembrane signaling molecules and receptors.
LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autosomal dominant lateral temporal epilepsy (ADTLE), characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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