Thermo Fisher Scientific MLLT1 Polyclonal Antibody
Western blot과 ELISA에 적합한 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. 1.85 mg/mL 농도의 액상 형태이며, PBS/glycerol buffer에 보관됩니다. MLLT1 단백질(aa 190-270)을 면역원으로 사용했습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 190–270 of human MLLT1 (NP_005925.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.85 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901452 |
Product Specific Information
- Positive Samples: Mouse thymus, Rat brain, Rat thymus
- Immunogen Sequence:
KTSKPHKVTK EHRERPRKDS ESKSSSKELE REQAKSSKDT SRKLGEGRLP KEEKAPPPKA AFKEPKMALK ETKLESTSPK G
Target Information
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene, resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins.
Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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