
Thermo Fisher Scientific PSMD2 Monoclonal Antibody (OTI1G8), TrueMAB
PSMD2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 면역세포염색(ICC/IF)에 적합합니다. 다양한 종(인간, 마우스, 랫, 개)에 반응하며, 고순도의 액상 항체로 안정적인 결과를 제공합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G8 |
| Immunogen | Full length human recombinant protein of human PSMD2 produced in HEK293T cell. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.58 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
The 20S core consists of four rings of 28 non-identical subunits (two alpha and two beta rings).
The 19S regulator includes a base (with six ATPase and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and are responsible for ATP/ubiquitin-dependent peptide cleavage in a non-lysosomal pathway.
A modified form, the immunoproteasome, processes class I MHC peptides.
This gene encodes one of the non-ATPase subunits of the 19S regulator lid and may also participate in the TNF signaling pathway due to its interaction with the TNF type 1 receptor.
A pseudogene has been identified on chromosome 1.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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