Thermo Fisher Scientific MYH7 Polyclonal Antibody
Human MYH7 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:1,000–1:2,500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 심근 및 골격근 연구용으로 적합.
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Thermo Fisher Scientific MYH7 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MYH7 (Recombinant protein control fragment, Product #RP-89004) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2644344 |
Product Specific Information
Immunogen sequence:
ALRKKHADSV AELGEQIDNL QRVKQKLEKE KSEFKLELDD VTSNMEQIIK AKANLEKMCR TLEDQMNEHR SKAEETQRSV NDLTSQRAKL QTENGELSRQ LDEKEALISQ LTRGKLTYTQ QLEDLKRQLE EEVKAKNALA HALQS
Ortholog sequence identity:
- Mouse: 100%
- Rat: 100%
Target Information
Muscle myosin is a hexameric protein composed of 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits.
The MYH7 gene encodes the beta (slow) heavy chain subunit of cardiac myosin, mainly expressed in human ventricular tissue and slow-twitch skeletal muscle fibers.
Expression levels vary with cardiac contractile velocity, thyroid hormone status, and hemodynamic load.
Mutations in MYH7 are linked to familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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