Thermo Fisher Scientific Human BAG4 Synthetic Peptide
인간 BAG4 단백질의 N-말단 서열을 기반으로 한 합성 펩타이드입니다. 항체 차단 실험에 사용 가능하며, 200 µg/mL 농도의 액상 형태로 제공됩니다. PBS 버퍼(pH 7.2, 0.1% BSA, 0.02% sodium azide)로 안정화되어 있으며, -20°C에서 보관합니다.
- 카탈로그번호
- PEP0050
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids at the amino terminus of human SODD.
PEP-0050 can be used as a blocking peptide with polyclonal antibody PA5-19925.
Target Information
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that interacts with various apoptosis and growth-related proteins such as BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors, and members of the heat shock protein 70 kDa family.
This protein contains a BAG domain near the C-terminus, which binds and inhibits the chaperone activity of Hsc70/Hsp70. It associates with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), thereby negatively regulating downstream cell death signaling.
Its regulatory role in cell death was demonstrated in epithelial cells that undergo apoptosis upon loss of integrin-mediated matrix contacts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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