Thermo Fisher Scientific Human Amyloid Precursor Protein Synthetic Peptide
인간 Amyloid Precursor Protein(APP) 유래 합성 펩타이드로, 항체 차단 실험에 사용 가능. 15개 아미노산 서열로 구성되어 있으며, PBS 버퍼(pH 7.2, 0.1% BSA) 내 액상 형태. APP 관련 연구 및 알츠하이머 질환 연구용에 적합.
- 카탈로그번호
- PEP0048
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Amyloid Precursor Protein Synthetic Peptide
Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human APP.
PEP-0048 can be used as a blocking peptide with polyclonal antibody PA5-19923.
Target Information
Amyloid Precursor Protein (APP), also known as Amyloid beta precursor protein, functions as a cell surface kinesin I membrane receptor mediating the axonal transport of beta-secretase and presenilin 1.
APP is important for neurite growth, neuronal adhesion, and axonogenesis. It is a 100–140 kDa transmembrane glycoprotein that exists as several isoforms resulting from alternative splicing.
Proteolytic cleavage of APP by beta- and gamma-secretases produces beta amyloid, the primary component of senile plaques—one of the major histopathologic features of Alzheimer’s disease.
Abnormal regulation and processing of APP also play roles in Down’s syndrome, early-onset familial Alzheimer’s disease, and cerebral hemorrhage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.