Thermo Fisher Scientific CXCL17 Polyclonal Antibody
CXCL17 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 시료에 반응하며 Western blot에 적합. 액상 형태로 1 mg/mL 농도, PBS 버퍼와 글리세롤 포함. CXCL17의 면역 및 염증 반응 연구에 활용 가능.
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Thermo Fisher Scientific CXCL17 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CXCL17 (Accession Q6UXB2), corresponding to amino acid residues R58–K108 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818794 |
Product Specific Information
Antibody detects endogenous levels of total CXCL17.
Target Information
CXCL17 is a chemokine that acts as a chemoattractant for monocytes, macrophages, and dendritic cells. It is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly tumor development. It also acts as an anti-inflammatory in the stomach and may contribute to innate defense against infections. CXCL17 activates the C-X-C chemokine receptor GPR35, inducing a rapid and transient rise in intracellular calcium levels. The 4-Cys form of CXCL17 exhibits higher chemoattractant potency on monocytes and macrophages than the 6-Cys form. Diseases associated with CXCL17 dysfunction include cholera.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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