
Thermo Fisher Scientific KLRC2/KLRC4 Polyclonal Antibody
KLRC2/KLRC4 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 IHC(P) 분석에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. PBS/glycerol 버퍼에 보관되며 연구용으로 사용됩니다.
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- PA599852
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KLRC2 (Accession P26717), corresponding to amino acid residues M1–Q40 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818785 |
Product Specific Information
Antibody detects endogenous levels of total KLRC2/4.
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They also regulate specific humoral and cell-mediated immunity. NK cells express several calcium-dependent (C-type) lectins implicated in NK cell function regulation.
The KLRC (NKG2) group encodes transmembrane proteins with a type II membrane orientation and a C-type lectin domain. The KLRC (NKG2) gene family resides within the NK complex, which contains several lectin genes preferentially expressed on NK cells.
KLRC2 alternative splice variants have been described, but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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