Thermo Fisher Scientific F-Box Only Protein 9 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.

This affinity-purified antibody is directed against human FBOX9 protein. A BLAST analysis suggests cross-reactivity with FBOX9 protein from human, dog, rat, and chimpanzee (100% homology with the immunizing sequence). Partial reactivity is expected with homologues from zebrafish, bovine, and mouse (94%), chicken (88%), and Xenopus laevis (82%). Reactivity is expected against all known isoforms of this protein, as the immunogen sequence is common to their carboxy-terminal ends. Reactivity against homologues from other sources is not known.

Target Information

FBXO9 (F-box protein 9) is a Ubl conjugation pathway protein containing one F-box domain and one TPR repeat. FBXO9 may act as a potential sepsis biomarker or therapeutic target. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which functions in phosphorylation-dependent ubiquitination.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.