Thermo Fisher Scientific ATP1B1 Polyclonal Antibody
ATP1B1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. Western blot과 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA529719
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 83–303 of Human Sodium Potassium ATPase Beta 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547193 |
Product Specific Information
- Recommended positive controls: K562, HL-60, mouse brain, rat brain
- Predicted reactivity: Mouse (90%), Rat (92%), Dog (91%), Pig (89%), Rabbit (87%), Sheep (91%), Rhesus Monkey (96%), Chimpanzee (99%), Guinea pig (86%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The ATP1B1 gene encodes the beta 1 subunit of the Na⁺/K⁺-ATPase, an integral membrane protein responsible for maintaining electrochemical gradients of sodium and potassium ions across the plasma membrane. These gradients are essential for osmoregulation, sodium-coupled transport, and electrical excitability of nerve and muscle cells. The enzyme consists of a large catalytic alpha subunit and a smaller glycoprotein beta subunit, which regulates the number of sodium pumps transported to the plasma membrane. Multiple genes encode the glycoprotein subunit, and alternatively spliced variants of ATP1B1 have been described.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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