Thermo Fisher Scientific LRRTM1 Polyclonal Antibody
LRRTM1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western Blot, ICC/IF, Flow Cytometry에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific LRRTM1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within mouse LRRTM1 aa 320–360/522 (Extracellular) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913514 |
Product Specific Information
- Positive Control: SH-SY5Y cell lysate, N2A cell lysate, rat brain tissue lysate
- Subcellular Location: Cell membrane, postsynaptic cell membrane
Target Information
The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and mediate presynaptic and postsynaptic glutamatergic differentiation. LRRTM1 and LRRTM2 are most potent at inducing presynaptic differentiation.
Each LRRTM protein is a type I transmembrane molecule containing ten extracellular leucine-rich repeats and a short intracellular tail, exhibiting a distinct developmental expression pattern.
LRRTM1 is a maternally suppressed gene associated paternally with handedness and schizophrenia.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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