Thermo Fisher Scientific Influenza A H1N1 HA Monoclonal Antibody (7H12F6)

Applications

Product Specifications

Product Specific Information

This antibody does not cross-react with swine-origin influenza A (S-OIV, H1N1) Hemagglutinin.

Target Information

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic.

Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins elicit immune responses that prevent infection or reduce viral replication.

The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain combining a triple assortment first identified in 1998 (human, swine, and avian influenza) with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of this new swine influenza virus compared with seasonal influenza A (H1N1) suggest limited human immunity, though older age groups may have partial protection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.