
Thermo Fisher Scientific IL1R2 Polyclonal Antibody
Mouse IL1R2 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody로, WB, IHC(F), Flow Cytometry에 적합. 항원 친화 크로마토그래피로 정제되었으며, 보존제 무첨가 PBS/trehalose 용액에 동결건조 형태로 제공. 연구용 전용 제품.
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Thermo Fisher Scientific IL1R2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
| Flow Cytometry (Flow) | 0.25 µg per million cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Sf21-derived recombinant mouse IL-1 RII (Phe14–Glu355, predicted) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609074 |
Product Specific Information
- In direct ELISAs, approximately 30% cross-reactivity with recombinant human IL-1 RII is observed.
- Less than 1% cross-reactivity with recombinant mouse IL-1 RI, recombinant rat IL-1 Rrp2, rmIL-18 R, and rmIL-18 R beta is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The IL1R2 gene encodes a cytokine receptor belonging to the interleukin 1 receptor family.
This protein binds IL1A, IL1B, and IL1R1/IL1RA, acting as a decoy receptor that inhibits ligand activity.
IL4 antagonizes IL1 activity by inducing expression and release of IL1R2.
This gene forms part of a cytokine receptor cluster on chromosome 2q12.
Two alternatively spliced transcript variants encoding the same protein are reported.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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