Thermo Fisher Scientific XRCC1 Monoclonal Antibody (OTI3C3), TrueMAB
Thermo Fisher Scientific의 XRCC1 Monoclonal Antibody (OTI3C3)는 인간 XRCC1 단백질을 인식하는 Mouse IgG1 항체로, WB 및 ICC/IF 실험에 적합합니다. 고순도 친화 크로마토그래피 정제, 무보존제 PBS 버퍼, 연구용 DNA 손상 복구 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C3 |
| Immunogen | Full length human recombinant protein of human XRCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair.
It is a 70 kDa protein associated with DNA repair enzymes such as poly (ADP-ribose) polymerase (PARP), DNA Ligase III, and DNA polymerase beta.
XRCC1 contains a BRCT domain (BRCA1 carboxyl terminus) that mediates protein-protein interactions with DNA ligase III-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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