Thermo Fisher Scientific DDX17 Recombinant Rabbit Monoclonal Antibody (ARC1413)
Recombinant rabbit monoclonal antibody targeting human DDX17 protein (clone ARC1413). Validated for WB, IHC(P), and ELISA applications. High purity via affinity chromatography, supplied in liquid form with PBS/glycerol buffer. Designed for research use...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1413 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 100–200 of human DDX17 (UniProt ID: Q92841) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.54 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849588 |
Product Specific Information
Immunogen sequence:
RGGGGLPPKK FGNPGERLRK KKWDLSELPK FEKNFYVEHP EVARLTPYEV DELRRKKEIT VRGGDVCPKP VFAFHHANFP QYVMDVLMDQ HFTEPTPIQC Q
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.
This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by the DDX5 gene, are more closely related to each other than to any other member of the DEAD box family.
This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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