Thermo Fisher Scientific S100A6 Recombinant Rabbit Monoclonal Antibody (016)
Recombinant rabbit monoclonal antibody specific to Mouse S100A6/Calcyclin/CACY. Suitable for WB, IHC, and ELISA. High purity, preservative-free formulation with consistent lot performance and enhanced specificity. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 016 |
| Immunogen | Recombinant Mouse S100A6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785597 |
Product Specific Information
- Preservative-free formulation. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed from immunoreactive rabbit DNA sequences.
- Advantages include improved specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity due to the larger rabbit immune repertoire.
- Specificity: Mouse S100A6/Calcyclin/CACY.
Target Information
The S100A6 protein belongs to the S100 family of calcium-binding proteins containing two EF-hand motifs. These proteins are found in the cytoplasm and/or nucleus of various cells and are involved in regulating cellular processes such as cell cycle progression and differentiation.
S100 genes form a cluster on chromosome 1q21 with at least 13 members. S100A6 may play roles in Ca²⁺-dependent insulin release, prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression have been linked to melanoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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