Thermo Fisher Scientific PTPRT Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PTPRT if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTPRT,uniProtId:O14522-3,ncbiNodeId:9606,antigenRange:387-495,antigenLength:1441,antigenImageFileName:PA5-53587_PTPRT_O14522-3_Rabbit.svg,antigenImageFileNamePDP:PA5-53587_PTPRT_O14522-3_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646137

Product Specific Information

Immunogen sequence: VHGPQNVEIV DIRARQLTLQ WEPFGYAVTR CHSYNLTVQY QYVFNQQQYE AEEVIQTSSH YTLRGLRPFM TIRLRLLLSN PEGRMESEEL VVQTEEDVPG AVPLESIQG

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 54%.

Target Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.