Thermo Fisher Scientific MAP2 Polyclonal Antibody
MAP2 단백질을 검출하는 Thermo Fisher Scientific의 다클론 항체로, 인간·마우스·랫트 반응성. WB, IHC, ICC 등 다양한 응용 가능. IgY 분획 정제, 액상 형태로 제공되며 신경세포 연구 및 알츠하이머 질환 연구에 적합.
- 카탈로그번호
- PA116751
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:10,000–1:20,000 | - |
| Immunohistochemistry (IHC) | - | 5 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000–1:5,000 | - |
| Immunocytochemistry (ICC/IF) | 1:5,000–1:10,000 | 3 publications |
| in situ PLA (PLA) | - | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Chimpanzee, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human construct of projection domain sequences, amino acids 377–1505 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Purification | IgY fraction |
| Storage Buffer | PBS |
| Contains | 0.035% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2138189 |
Product Specific Information
In Western blot, bands can be seen at approximately 280 kDa representing MAP2a and MAP2b.
Bands may also be seen at approximately 70 kDa representing MAP2c.
Target Information
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. Its expression is developmentally regulated, arising from alternative splicing of a single gene. MAP2 is involved in microtubule assembly, an essential step in neurogenesis.
In rat and mouse, MAP2 products are neuron-specific cytoskeletal proteins enriched in dendrites, playing a role in determining and stabilizing dendritic shape during neuron development.
MAP2 is useful for studies of neuron structure in normal and malignant brain tissue and in degenerative diseases such as Alzheimer’s Disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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