Thermo Fisher Scientific SUZ12 Monoclonal Antibody (K.6.9)
SUZ12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Monoclonal Antibody (Clone K.6.9). Western blot, IHC, ICC, IP, ChIP 등 다양한 응용 가능. 인간, 마우스, 랫트 등 반응성. 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Thermo Fisher Scientific SUZ12 Monoclonal Antibody (K.6.9)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:800 | - |
| Immunoprecipitation (IP) | 1:100 | - |
| ChIP assay (ChIP) | 1:100 | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K.6.9 |
| Immunogen | Synthetic peptide corresponding to the sequence of the human SUZ12 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 84 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10987451 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
SUZ12 (polycomb protein SUZ12) is a zinc finger gene identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1.
SUZ12 is also a component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene.
The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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