Thermo Fisher Scientific CDH12 Recombinant Rabbit Monoclonal Antibody (403)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.

Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody specifically recognizes Human Cadherin-12/CDH12.

Target Information

CDH12 is a type II classical cadherin from the cadherin superfamily, mediating calcium-dependent cell-cell adhesion. Mature cadherins contain:

• Large N-terminal extracellular domain
• Single membrane-spanning domain
• Small, conserved C-terminal cytoplasmic domain

Type II cadherins lack the HAV recognition sequence found in type I cadherins. CDH12 is expressed specifically in the brain, suggesting a role in neuronal development, particularly during synaptogenesis.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음)