Thermo Fisher Scientific TRAF4 Polyclonal Antibody
TRAF4 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 및 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 225 and 275 of Human TNF Receptor-Associated Factor 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The tumor necrosis factor (TNF) receptor superfamily consists of several type I integral membrane glycoproteins sharing homology in their cysteine-rich extracellular domains. Members include TNF-RI, TNF-RII, and CD40. Ligands for these receptors can be small secreted proteins (e.g., TNF) or type II integral membrane proteins (e.g., CD40L). Activation of TNF-R or CD40 induces nuclear translocation of NFκB, a process involving members of the TRAF (TNF receptor-associated factor) family. Four TRAF members—TRAF1, TRAF2, TRAF3, and TRAF4—have been identified. TRAF4, originally termed CART1, is specifically expressed in breast carcinomas and localized to the nucleus in such tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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