
Thermo Fisher Scientific TRAF4 Polyclonal Antibody
TRAF4 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot과 Immunoprecipitation에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 225 and 275 of Human TNF Receptor-Associated Factor 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that share homology in their cysteine-rich extracellular domains. Members include TNF-RI, TNF-RII, and CD40. Ligands for these receptors may be small secreted proteins such as TNF, or type II integral membrane proteins like CD40L. Although the signal transduction mechanism of the TNF receptor superfamily is not fully understood, activation of TNF-R or CD40 induces nuclear translocation of NFκB. Members of the TRAF (TNF receptor-associated factor) family, including TRAF1, TRAF2, TRAF3, and TRAF4, are involved in this process. TRAF4, originally termed CART1, is specifically expressed in breast carcinomas and localized to the nucleus in these tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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