Thermo Fisher Scientific SDHB Polyclonal Antibody
Thermo Fisher Scientific의 SDHB Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 미토콘드리아 내 복합체 II 연구용으로 적합합니다. Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능하며 항원 친화 크로마토그래피로 정제된 고품질 항체입니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human SDHB amino acids 100–280 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913241 |
Product Specific Information
- Positive Control: Rat liver tissue, human liver tissue, mouse liver tissue, 293T, HT-29, HeLa, rat heart tissue, human kidney tissue, human skin tissue, mouse colon tissue
- Subcellular Location: Mitochondrion
Target Information
Complex II of the respiratory chain is specifically involved in the oxidation of succinate and carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, supporting a link between mitochondrial dysfunction and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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