Thermo Fisher Scientific CBX8 Monoclonal Antibody (OTI6D9), TrueMAB
Human CBX8 단백질(아미노산 1-260)을 항원으로 한 Mouse IgG2b 단클론 항체. Western blot에 최적화되어 있으며, 무보존제, 동결건조 형태로 제공. 연구용으로 Polycomb group 복합체 관련 유전자 발현 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–260 of human CBX8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
CBX8 is a component of the Polycomb group (PcG) multiprotein PRC1-like complex, which maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development.
The PcG PRC1 complex mediates monoubiquitination of histone H2A (Lys-119), leading to heritable chromatin modifications that regulate gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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