Thermo Fisher Scientific Human BMPR1A (ALK3), GST Tag Recombinant Protein

Thermo Fisher Scientific Human BMPR1A (ALK3), GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

For maximum recovery, please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg, and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted.
For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots; aliquots below 20 µL are not recommended.
Never store a kinase diluted. If properly stored at −80°C, this product is guaranteed for 6 months from the date of purchase.

Protein Form: Catalytic

Target Information

BMPR1A is a Type I member of the TGF-beta receptor superfamily of transmembrane serine/threonine kinases that phosphorylates intracellular SMADs in response to bone morphogenic proteins.
These receptors are closely related to activin receptors ACVR1 and ACVR2. The ligands of these receptors belong to the TGF-beta superfamily.
TGF-betas and activins transduce their signals through heteromeric complexes with two types of serine/threonine kinase receptors:

• Type I receptors (~50–55 kDa)
• Type II receptors (~70–80 kDa)

Type II receptors bind ligands in the absence of type I receptors but require their respective type I receptors for signaling, while type I receptors require their respective type II receptors for ligand binding.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.