Thermo Fisher Scientific Urokinase VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1008)
Thermo Fisher Scientific의 Urokinase VHH-8His-Cys-tag 재조합 알파카 단일클론 항체. 인간 Urokinase(PLAU)를 인식하며 ELISA에 적합. CHO 세포에서 발현된 고순도 항체로, 금속 킬레이트 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1008 |
| Immunogen | Recombinant Human PLAU |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation.
A specific polymorphism in this gene may be associated with late-onset Alzheimer’s disease and also with decreased affinity for fibrin-binding.
This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen.
Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative (HMW-uPA) connected by a disulfide bond.
HMW-uPA can be further processed into LMW-uPA by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment.
LMW-uPA is proteolytically active but does not bind to the uPA receptor.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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