
Thermo Fisher Scientific PTCH VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1006)
Thermo Fisher의 PTCH VHH-8His-Cys-tag 재조합 알파카 단일클론 항체. 인간 PTCH1 단백질을 인식하며, Direct ELISA에 적합. CHO 세포에서 발현된 VHH 형식의 항체로, 금속-킬레이트 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1006 |
| Immunogen | Recombinant Human PTCH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins.
This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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