Thermo Fisher Scientific OAZ3 Polyclonal Antibody
OAZ3 단백질을 인식하는 토끼 폴리클로날 항체로, 인간·마우스·랫트에 반응합니다. Western blot에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 세포 내 폴리아민 조절 및 생식세포 연구용에 적합합니다.
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Thermo Fisher Scientific OAZ3 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human OAZ3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719359 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity is >95% (by SDS-PAGE).
Target Information
The antizyme family consists of small proteins involved in regulating polyamine biosynthesis such as putrescine, spermidine, and spermine, which are important for cell growth and division.
OAZ3 (Ornithine decarboxylase antizyme 3) is a 187-amino-acid protein belonging to the ODC antizyme family. It likely plays a key role in spermatogenesis by controlling intracellular polyamine levels in haploid germ cells through binding and destabilizing ornithine decarboxylase.
Mutations in the AZ3 gene are not a common cause of male infertility, and the normal AZ3 protein does not accelerate ornithine decarboxylase degradation. AZ3 expression begins sharply in early spermatids, peaks in later stages, and disappears in spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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