Thermo Fisher Scientific CD123 Polyclonal Antibody
인간 CD123(IL-3Rα)을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 적합. 고순도 Protein A 정제, 0.5 mg/mL 농도의 액상 형태. PBS/BSA buffer에 보존되며 -20°C에서 안정 저장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CD123 Polyclonal Antibody
Applications
- Western Blot (WB): 3–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A portion of amino acids 120–170 of human IL-3Rα (CD123) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540960 |
Target Information
IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and forms a heterodimer with the common beta (CDw131) subunit. It mediates signal transduction of Interleukin-3. Heterodimerization of IL-3Ra and IL-3Rb is induced by IL-3, necessary for receptor activation but not for high-affinity binding. IL-3Ra is reported to be overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells, making it a potential target for novel therapeutic agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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