Thermo Fisher Scientific NUP214 Polyclonal Antibody

Thermo Fisher Scientific NUP214 Polyclonal Antibody

Applications

• Western Blot (WB): 1:2,000–1:10,000
• Immunoprecipitation (IP): 2–5 µg/mg lysate

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm.
Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells.
This gene is a member of the FG-repeat-containing nucleoporins.
The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport.
The 3′ portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6;9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome.
Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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