Thermo Fisher Scientific GPR17 Monoclonal Antibody (OTI9D6), TrueMAB
GPR17 단백질을 인식하는 Mouse IgG1 단일클론 항체로, 인간·마우스·랫트 반응성. 면역조직화학(IHC) 적용 가능. 동결건조 형태로 제공되며, PBS 버퍼(8% trehalose) 포함. 연구용으로만 사용 가능.
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Thermo Fisher Scientific GPR17 Monoclonal Antibody (OTI9D6), TrueMAB
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution
- 1:150–1:300
Publications
- [참고 문헌 정보 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9D6 |
| Immunogen | Synthetic peptide |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The G-protein-coupled receptor (GPCR) superfamily comprises approximately 600–1,000 members and represents the largest known class of molecular targets with therapeutic relevance.
GPR17 is an orphan G protein-coupled receptor involved in oligodendrocyte differentiation and myelination in the central nervous system. It is expressed in brain, kidney, heart, and umbilical vein endothelial cells.
GPR17 exhibits dual specificity for uracil nucleotides and cysteinyl leukotrienes, signaling through G(i) and inhibiting adenylyl cyclase. It may mediate brain damage following ischemia through these signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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