Thermo Fisher Scientific KCNJ3 Monoclonal Antibody (OTI1C5), TrueMAB
KCNJ3 단백질을 인식하는 Mouse monoclonal 항체로, WB 및 ICC/IF에 적합합니다. Human, Mouse, Rat, Dog에 반응하며, Lyophilized 형태로 제공됩니다. G 단백질 조절 칼륨 채널 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 279–501 of human KCNJ3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This potassium channel is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium ions to flow into rather than out of the cell. Their voltage dependence is regulated by extracellular potassium concentration; as external potassium increases, the voltage range for channel opening shifts to more positive potentials. The inward rectification mainly results from blockage of outward current by internal magnesium. This receptor is essential for regulating cardiac rhythm.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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