Thermo Fisher Scientific eIF4E Polyclonal Antibody
Rabbit polyclonal antibody against Human eIF4E for IHC (Paraffin) applications. Recognizes amino acids 161–217 of eIF4E. High purity (>95%) and antigen affinity purified. Supplied as liquid, 1 mg/mL in PBS with glycerol and sodium azide. For research u...
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 161–217 of Human eIF4E |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803439 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export.
All eukaryotic cellular mRNAs are blocked at their 5′ ends with the 7-methylguanosine cap structure (m7GpppX).
eIF4E is a eukaryotic translation initiation factor that directs ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide existing both freely and as part of the EIF4F complex.
The EIF4E polypeptide is the rate-limiting component in eukaryotic translation and participates in the mRNA–ribosome binding step of protein synthesis.
Other subunits of EIF4F include EIF4A (50 kD, ATPase and RNA helicase) and EIF4G (220 kD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 이미지: PA5-86679_eIF4E_P06730-1_Rabbit.svg / PA5-86679_eIF4E_P06730-1_Rabbit_PDP.jpeg)
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