Thermo Fisher Scientific ZDHHC16 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 286-314 amino acids from the C-terminal region of human ZDH16. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZDHHC16,uniProtId:Q969W1-1,ncbiNodeId:9606,antigenRange:286-314,antigenLength:377,antigenImageFileName:PA5-48669_ZDHHC16_Q969W1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-48669_ZDHHC16_Q969W1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2634126

Product Specific Information

Predicted to react with monkey and mouse based on sequence homology.

Target Information

ZDHHC16 (zinc finger, DHHC-type containing 16), also known as APH2, is a 377 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one DHHC-type zinc finger. Existing as multiple alternatively spliced isoforms, ZDHHC16 interacts with c-Abl and catalyzes the conversion of Palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Via its association with c-Abl, ZDHHC16 may be involved in the regulation of apoptosis. The gene encoding ZDHHC16 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman`s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.