Thermo Fisher Scientific Npr2 Polyclonal Antibody
Thermo Fisher Scientific의 Npr2 Polyclonal Antibody는 마우스 Npr2 단백질을 인식하는 Rabbit IgG 항체입니다. Western blot에 적합하며, KLH 결합 합성 펩타이드로 면역화되었습니다. 단백질 A 및 항원 친화 크로마토그래피로 정제되어 높은 특이성을 제공합니다.
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Applications
- Western Blot (WB): 1:1,000 희석 비율로 테스트됨
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 480–509 from the central region of mouse Npr2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634131 |
Product Specific Information
Predicted to react with rat based on sequence homology.
Target Information
This gene encodes natriuretic peptide receptor B (NPR2), one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains:
- Extracellular ligand-binding domain
- Single membrane-spanning region
- Intracellular protein kinase homology domain
- Helical hinge region involved in oligomerization
- Carboxyl-terminal guanylyl cyclase catalytic domain
NPR2 is the primary receptor for C-type natriuretic peptide (CNP), and ligand binding greatly increases guanylyl cyclase activity. Mutations in this gene are associated with acromesomelic dysplasia, Maroteaux type.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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