Thermo Fisher Scientific Carbonic Anhydrase XI Polyclonal Antibody
Thermo Fisher Scientific의 Carbonic Anhydrase XI 폴리클로날 항체는 인간 시료에 반응하며 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 뇌 조직 내 Carbonic Anhydrase XI 단백질 연구에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–311 of CA11 (Uniprot ID: O75493) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152680 |
Product Specific Information
- Recommended positive control: A431
- Predicted reactivity: Pig (96%), Sheep (97%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
Carbonic Anhydrase XI (CA11, CA XI) is a member of the carbonic anhydrases (CAs) family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide.
CA XI participates in biological processes such as respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.
Although likely secreted, CA XI has radical changes at conserved active site residues, making it unlikely to have catalytic activity. It shares properties with other acatalytic isoforms CA VIII and CA X and is most abundantly expressed in the brain, suggesting a role in the central nervous system.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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