Thermo Fisher Scientific CCT8 Polyclonal Antibody
Rabbit polyclonal antibody against human CCT8 (TCP-1 theta) for WB, IHC, and IP applications. Recognizes region 448–498 of CCT8. Recommended shelf life 1 year. Suitable for research use only.
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Thermo Fisher Scientific CCT8 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 448 and 498 of human Chaperonin Containing TCP1, Subunit 8 (TCP-1 theta, UniProt ID: P50990-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan
Target Information
TCP-1 theta is the theta subunit of the CCT (chaperonin containing TCP1 complex), a molecular chaperone abundant in the eukaryotic cytosol. It assists in protein folding upon ATP hydrolysis and may play a role in assembly of the BBsome complex involved in ciliogenesis and vesicle transport. TCP-1 theta also contributes to the folding of actin and tubulin. The intact CCT complex consists of eight polypeptides forming a double ring structure and is essential for folding of proteins such as the VHL tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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