Thermo Fisher Scientific CBS Polyclonal Antibody
Human CBS 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도와 재현성을 제공합니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CBS. Recombinant protein control fragment (Product # RP-98844) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639331 |
Product Specific Information
Immunogen sequence:
GGSVKDRISL RMIEDAERDG TLKPGDTIIE PTSGNTGIGL ALAAAVRGYR CIIVMPEKMS SEKVDVLRAL GAEIVRTPTN ARFDSPESHV GVAWRLKNEI PNSHILDQYR NASNPLAHYD TTADEILQQC DGKLDMLVAS VGTGGTITGI GAPHR
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 92%
Target Information
This antibody targets the only known pyridoxal phosphate-dependent enzyme that contains heme. It is an important regulator of hydrogen sulfide, particularly in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide acts as a gasotransmitter with signaling and cytoprotective effects, including neuromodulation and neuronal protection against hypoxic injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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