Thermo Fisher Scientific DRG1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DRG1. Recombinant protein control fragment (Product #RP-91361). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DRG1,uniProtId:Q9Y295-1,ncbiNodeId:9606,antigenRange:164-306,antigenLength:367,antigenImageFileName:PA5-51540_DRG1_Q9Y295-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51540_DRG1_Q9Y295-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640794

Product Specific Information

Immunogen sequence: ELEGFGIRLN SKPPNIGFKK KDKGGINLTA TCPQSELDAE TVKSILAEYK IHNADVTLRS DATADDLIDV VEGNRVYIPC IYVLNKIDQI SIEELDIIYK VPHCVPISAH HRWNFDDLLE KIWDYLKLVR IYTKPKGQLP DYT

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (PubMed:29915238, PubMed:23711155). Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions (PubMed:23711155). When hydroxylated at C-3 of Lys-22 by JMJD7, may bind to RNA and play a role in translation (PubMed:19819225, PubMed:29915238). Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions (PubMed:28855639). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.