
Thermo Fisher Scientific DRG1 Polyclonal Antibody
Thermo Fisher Scientific DRG1 Polyclonal Antibody는 인간, 마우스, 랫트 DRG1 단백질을 검출하기 위한 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DRG1. Recombinant protein control fragment (Product #RP-91361) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640794 |
Product Specific Information
- Immunogen sequence:
ELEGFGIRLN SKPPNIGFKK KDKGGINLTA TCPQSELDAE TVKSILAEYK IHNADVTLRS DATADDLIDV VEGNRVYIPC IYVLNKIDQI SIEELDIIYK VPHCVPISAH HRWNFDDLLE KIWDYLKLVR IYTKPKGQLP DYT - Highest antigen sequence identity: Mouse - 100%, Rat - 100%
Target Information
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (PubMed:29915238, PubMed:23711155).
Appears to have intrinsic GTPase activity stimulated by ZC3H15/DFRP1 binding, likely increasing affinity for potassium ions (PubMed:23711155).
When hydroxylated at C-3 of Lys-22 by JMJD7, may bind RNA and play a role in translation (PubMed:19819225, PubMed:29915238).
Binds microtubules and promotes polymerization and stability required for mitotic spindle assembly during prophase to anaphase transition.
GTPase activity is not necessary for these microtubule-related functions (PubMed:28855639). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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