Thermo Fisher Scientific IGFBP3 Monoclonal Antibody (OTI3B9), TrueMAB
인간 IGFBP3 단백질을 인식하는 단클론 항체로 Western blot에 적합합니다. 동결건조 형태로 제공되며 재구성 시 1 mg/mL 농도로 사용 가능합니다. 무보존제 PBS 버퍼에 담겨 있으며, -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 28–297 of human IGFBP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
IGFBP3 belongs to the insulin-like growth factor binding protein (IGFBP) family. It encodes a protein containing both an IGFBP domain and a thyroglobulin type-I domain.
This protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either IGF-I or IGF-II. The complex circulates in plasma, prolonging IGF half-life and modulating receptor interactions.
Multiple isoforms exist due to alternative splicing. Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Acid-Labile Subunit Deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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