Thermo Fisher Scientific KCNIP2 Monoclonal Antibody (OTI10F10), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of ~1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Voltage-gated potassium (Kv) channels are essential for potassium currents in the heart and central nervous system.

• In the heart: Kv4 channels contribute to the repolarization phase of the action potential.
• In the brain: These channels prevent reverse-propagation of action potentials.

KChIPs (Kv channel interacting proteins) are calcium-binding proteins associated with Kv4 channels, modulating their function.
Known KChIPs include:

1. KChIP1 – expressed in the brain
2. KChIP2 – expressed in brain, heart, and lung; three isoforms (a, b, c)
3. KChIP3 – also known as calsenilin or DREAM; expressed in brain and testis

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.