Thermo Fisher Scientific ARMET Polyclonal Antibody, Biotin
ARMET 단백질을 인식하는 Biotin 결합 토끼 폴리클로날 항체로, Western blot, IHC, ELISA, IP에 적합합니다. 사람, 마우스, 랫트에 반응하며, Affinity chromatography로 정제되었습니다. 연구용으로 ER 스트레스 관련 단백질 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 80–120 on human Mesencephalic astrocyte-derived neurotrophic factor (MANF/ARMET). |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The ARMET (also known as MANF) protein is localized in the endoplasmic reticulum and Golgi apparatus, and is also secreted. Reduced expression increases susceptibility to ER stress-induced cell death and promotes cell proliferation. Initially thought to have a longer N-terminus with an arginine-rich region, later evidence supports a smaller open reading frame without the arginine tract. Polymorphisms previously associated with tumors were later found to occur in normal tissues, indicating they are not tumor-specific.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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