Thermo Fisher Scientific HNRNPL Monoclonal Antibody (OTI2E4), TrueMAB
HNRNPL 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI2E4). Western blot과 IHC(P)에서 검증됨. 인간 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. PBS, BSA, glycerol, sodium azide 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 270–502 of human HNRNPL produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Heterogeneous nuclear RNAs (hnRNAs), including mRNA precursors and mature mRNAs, are associated with specific proteins to form heterogeneous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L (HNRNPL) is among the proteins stably associated with hnRNP complexes and, along with other hnRNP proteins, plays a major role in the formation, packaging, processing, and function of mRNA. HNRNPL is present in the nucleoplasm as part of the HNRNP complex, but HNRNP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies mRNA transport from the nucleus to the cytoplasm. Since HNRNP proteins shuttle between the nucleus and cytoplasm, they may also have cytoplasmic functions. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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