Thermo Fisher Scientific PON3 Monoclonal Antibody (OTI4H9), TrueMAB
인간 PON3 단백질(아미노산 30–319)을 항원으로 제작된 마우스 모노클로날 항체입니다. Western blot에 1:500 희석으로 사용 가능하며, 무보존제 PBS 용액에 동결건조 형태로 제공됩니다. 연구용으로 PON3 관련 심혈관 연구 및 단백질 분석에 적합합니다.
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Thermo Fisher Scientific PON3 Monoclonal Antibody (OTI4H9), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 30–319 of human PON3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments with this carrier-free antibody, perform an additional desalting step.
Recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Paraoxonase-1 (PON1) is a calcium-dependent ester hydrolase associated with apoA-I in HDL and prevents oxidation of LDL. Variations in the PON1 gene are linked to coronary artery disease.
PON2 provides intracellular protection against oxidative damage, while PON3, similar to PON1, differs in substrate specificity and contributes to reducing atherosclerosis risk.
Human PON3 shares three conserved cysteine residues with PON1, indicating their functional importance.
PON1-based catalytic scavengers may offer protection against organophosphate intoxication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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